Type II cellular rejection is characterized by mononuclear cells which are present under the vascular endothelium and caution should be taken not to confuse with the presence of the lymphocytes in the adventitia only. Only in rare cases do edema and of endothelium and vesselâ€™s intima or degeneration is found as a characteristic of type II T-cell rejection. In type III cellular mediated rejection, focal myocyte necrosis is witnessed and this is caused by infiltration of transmural mononuclear cells (Cohen, 2007). There are several locations where acute cellular rejection can be found including the tubules, the interstitium, arteries and the glomeruli.
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