The macula is characterized by a red spot in the retinal area of the eye which occurs because of the accumulation of gangliosides in the suffererâ€™s brain. The red spot is the only normal part of the retina that can be observed by ophthalmologists to determine whether a child suffers from Tay-Sachs. Other techniques that can be used in the genetic diagnosis of the disease include microscopic analysis of the bodyâ€™s neural network and molecular diagnostic techniques that analyze autosomal genes in the carrierâ€™s body
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