Numerous bonding procedures contribute to the adsorption of proteins, including positioning and ability to easily revolve. Higher vitronectin adsorption was noted on nano-phase ceramics, and it was seen to be unfolded to a higher extent to reveal more osteoblast adhesive epitopes than the molecules on normal ceramics. This cell bond process, due to shell characteristics, was also seen on nanophase ceramics in ï¬bronectin (Vance et al. 2004). Generally, nano-featured surfaces offer a greater surface area that influence protein bonding characteristics and increases cell adhesion.
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