Biomimetic approaches in bone tissue reconstruction

According to the gold model of autologous bone graft, the model contracted bone implant must be “osteoinductive, osteoconductive and osteogenic” (Laurencin et al. 2006, p. 52). Osteoinductive scaffolds provide spatial, bio-chemical, and physical stimuli to instigate stem cells or progenitor cells towards osteoblastic family. Osteoconductivity needs biocompatible implants to encourage the attachment, migration, survival, and supply of osteogenic cells. Osteogenic implants comprise of progenitor or osteogenic stem cells for bone redevelopment.

To satisfy these criteria, bone tissue reconstruction uses a biomimetic approach which may comprise biomaterial supports, physical and biochemical stimuli, vascularization, stem cells, and recapitulating the ordered construction of original ECM to produce functional bone tissues. Such biomimetic efforts comprise selecting bio-materials within the original bone structure, constructing poly-scale models in scaffold particularly with nanoscale elements, and integrating growth factors, stem cells and/or vascularization to offer a bio-mimetic opening for instigating bone reconstruction and regeneration. This review focuses on mirroring three-dimensional organization of bone construction with tissue modelling at the nano-phase.

Don't use plagiarized sources. Get Your Custom Essay on
Biomimetic approaches in bone tissue reconstruction
Just from $9/Page
Order Essay
Place your order
(550 words)

Approximate price: $22

Calculate the price of your order

550 words
We'll send you the first draft for approval by September 11, 2018 at 10:52 AM
Total price:
The price is based on these factors:
Academic level
Number of pages
Basic features
  • Free title page and bibliography
  • Unlimited revisions
  • Plagiarism-free guarantee
  • Money-back guarantee
  • 24/7 support
On-demand options
  • Writer’s samples
  • Part-by-part delivery
  • Overnight delivery
  • Copies of used sources
  • Expert Proofreading
Paper format
  • 275 words per page
  • 12 pt Arial/Times New Roman
  • Double line spacing
  • Any citation style (APA, MLA, Chicago/Turabian, Harvard)

Our guarantees

Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.

Money-back guarantee

You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.

Read more

Zero-plagiarism guarantee

Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.

Read more

Free-revision policy

Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.

Read more

Privacy policy

Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.

Read more

Fair-cooperation guarantee

By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.

Read more
error: Content is protected !!
Open chat
Need assignment help? You can contact our live agent via WhatsApp using +1 718 717 2861

Feel free to ask questions, clarifications, or discounts available when placing an order.
  +1 718 717 2861           + 44 161 818 7126           [email protected]
  +1 718 717 2861           + 44 161 818 7126           [email protected]